The Depew Fire Department is a completely volunteer, not-for-profit organization that was established to protect the citizens of the Village of Depew at times of emergency. The Depew Fire Department handles all fires in the Depew area and also performs rescue operations. The Depew Fire Department also responds to neighboring fire departments and districts when they are in need of firematic assistance. The Depew Fire Department remains the largest staffed fire department in the County of Erie.