Conveniently Located Hotel in La Mesa, CAOn the tree-lined streets of La Mesa, Holiday Inn Express La Mesa is a full-service hotel perfect for both corporate and leisure travel. This prime property is centrally located in San Diego County, only minutes from downtown with easy access to many industries and attractions of the city. While you're here, enjoy the views at one of our many nearby parks such as Mountain Helix Park, Mission Trails Regional Park, or Cowles Mountain. In the mood for entertainment? Check out some of the local eateries and shops at Grossmont Center or a concert at Viejas Arena or SDCCU Stadium. Visit us yearly for fun events like San Diego Comic Con. We are also within close proximity to medical facilities such as Sharp Grossmont Hospital, Alvarado Hospital, and Kaiser Permanente.The Holiday Inn Express San Diego - La Mesa has you covered if you're in the area for one of the many events that take place in our city. Cheer on your team while they compete against San Diego State University, San Diego Christian College, Grossmont College, or Cuyamaca College, or compete in a tournament at Santee Sportsplex or Joan Kroc Corps Community Center, all located within nine miles of our LA Mesa hotel. state-of-the-art fitness center, a heated outdoor pool and spacious guest rooms, Holiday Inn Express provides the perfect place to stay for any trip to San Diego!