Holiday Inn St Louis SW - Route 66, an IHG Hotel

Holiday Inn St Louis SW - Route 66, an IHG Hotel
10709 Watson Road
St. Louis, MO 63127
M-Su 24hr

Monday: 
12:00 am – 12:00 am
Tuesday: 
12:00 am – 12:00 am
Wednesday: 
12:00 am – 12:00 am
Thursday: 
12:00 am – 12:00 am
Friday: 
12:00 am – 12:00 am
Saturday: 
12:00 am – 12:00 am
Sunday: 
12:00 am – 12:00 am


Get your kicks on Route 66. Welcome to our fully renovated hotel and conference center, completed in 2023! Full-service, free parking, and pet friendly! Our property features room to spread out in a vibrant lobby with spaces to gather, relax, and work. The all-new courtyard boasts a heated pool, cabanas, and fireplaces with cozy seating and plenty of natural light to feel refreshed! Enjoy yard games under the string lights on the patio or work out in our new Fitness Center overlooking it all! Located on historic Route 66 at highway I-44 and I-270, just 14 miles from the Gateway Arch! We are centrally located to everything St. Louis has to offer and are minutes from top attractions: experience a St. Louis CITY SC game at CITYPARK, visit the St. Louis Zoo, Science Center, Missouri Botanical Gardens, Magic House, Six Flags or World Wide Technology Soccer Park. The hotel is just a short drive to Maritz, Webster University, Harris-Stowe, St. Louis University, and Washington University. Just a few miles to top medical centers, Barnes Jewish Hospital, St. Louis Children's Hospital, SSM, and Mercy Hospitals. Welcoming all travelers to our 214-room hotel and 15,500 square feet of space for your next event. Sunset Event Space, operated by Twisted Tree, is the perfect spot to book your wedding or special event. Start your day at Wakey Wakey and then enjoy lunch or dinner at Award-winning Twisted Tree Steakhouse adjacent to the hotel.

Payment Options

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